Pierre-Antoine Billon trained at Cours Florent and Ecole Thibault de Montalembert. He was directed by Thibault de Montalembert at Théâtre de la Bastille in A.D.N, by Dennis Kelly, followed by C’est l’anniversaire de Michelle mais elle a disparu, by Philippe Minyana, directed by Mats Besnardeau and Guillaume Delvingt at Vingtième Théâtre. Sarah Tick then directed him at Théâtre de Belleville in Les Rêves, by Ivan Viripaeiv, and then in Pourquoi mes frères et moi on est partis… by Hedi Tillette de Clermont-Tonnerre at the Condition des Soies, in Avignon, followed by a tour in 2017. He was then once again directed by Thibault de Montalembert in Le Zoo de Monsieur Vanel, for Arte. He performed in Hélène Babu’s production of The Seagull at CDN de Cherbourg and CDDB de Lorient, followed by a production of Les Fâcheux on tour and at Théâtre de Versailles.
He became part of Dramaticules in March 2017 in a replacement role on their production of Don Quichotte. He played the role of Horatio in Hamlet, based on the work by William Shakespeare, first performed in November 2018 at Théâtre de Châtillon. In Pinocchio, which also premiered at Théâtre de Châtillon in Octobre 2020, he played the roles of Fox and Lucignolo.